Publications

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* Co-first authors

2020

24. Shaokun Shu*, Hua-Jun Wu*, Jennifer Y. Ge, …, Franziska Michor, Kornelia Polyak. Synthetic lethal and resistance interactions with BET bromodomain inhibitors in triple-negative breast cancer. Molecular cell 2020 Jun 18;78(6):1096-1113.e8. doi: 10.1016/j.molcel.2020.04.027. Epub 2020 May 15.

2019

23. Weiwei Zhang, Ziyi Li, Nana Wei, Hua-Jun Wu, Xiaoqi Zheng. Detection of differentially methylated CpG sites between tumor samples with uneven tumor purities. Bioinformatics. 2019 Nov 26. pii: btz885. doi: 10.1093/bioinformatics/btz885.

2018

22. Kunihiko Hinohara*, Hua-Jun Wu*, Sébastien Vigneau, …, Franziska Michor and Kornelia Polyak. The KDM5B histone demethylase links cellular transcriptomic heterogeneity to therapeutic resistance. Cancer Cell. 2018 Nov 21; doi:10.1016/j.ccell.2018.10.014

21. Vicky A. Appleman, Hyun Jung Jun, Hua-Jun Wu*, …, Franziska Michor, Timothy J. Mitchison and Al Charest. A PDGFRα-driven mouse model of glioblastoma reveals a stathmin1-mediated mechanism of sensitivity to vinblastine. Nature Communications. 2018 Aug 6;9(1):3116.

20. Patrick J. Cimino, Youngmi Kim, Hua-Jun Wu, …, Franziska Michor and Eric Holland. Increased HOXA5 expression provides a selective advantage for gain of whole chromosome 7 in IDH-wildtype glioblastoma. Genes & Development. 2018 Apr 1;32(7-8):512-523.

2017

19. Lin Han, Hua-Jun Wu*, Haiying Zhu, …, Sherman M. Weissman, Franziska Michor, Rong Fan, Xinghua Pan. Bisulfite-independent analysis of CpG island methylation enables genome-scale stratification of single-cells. Nucleic Acids Research. 2017 Jun 2;45(10):e77.

18. Markus Riester*, Hua-Jun Wu*, Ahmet Zehir, Mithat Gönen, Andre L Moreira, Robert J Downey, Franziska Michor. Distance in cancer gene expression from stem cells predicts patient survival. PloS one. 2017 Mar 23;12(3):e0173589.

17. Xiaoqi Zheng, Naiqian Zhang, Hua-Jun Wu and Hao Wu. Estimating and accounting for tumor purity in cancer methylation microarray analysis. Genome Biology. 2017 Jan 25;18(1):17.

2016

16. Hua-Jun Wu* and Franziska Michor. A computational strategy to adjust for copy number in tumor Hi-C data. Bioinformatics. 2016 Dec 15;32(24):3695-3701.

15. Nitin Mahajan, Hua-Jun Wu, Richard L. Bennett, Catalina Troche, Jonathan D. Licht, Jason D. Weber, Leonard B. Maggi Jr., and Michael H. Tomasson. Sabotaging of the oxidative stress response by an oncogenic noncoding RNA. The FASEB Journal. 2016 Online.

2015

14. Naiqian Zhang*, Hua-Jun Wu*, Weiwei Zhang, Jun Wang, Hao Wu, and Xiaoqi Zheng. Predicting tumor purity from methylation microarray data. Bioinformatics. 2015 Nov 1;31(21):3401-5.

2014

13. Xiaoqi Zheng, Qian Zhao, Hua-Jun Wu*, …, Yong Zhang, Xiaole Shirley Liu. MethylPurify: tumor purity deconvolution and differential methylation detection from single tumor DNA methylomes. Genome Biology. 2014 Aug 7;15(8):419.

2013

12. Hua-Jun Wu*, Zhi-Min Wang*, Meng Wang and Xiu-Jie Wang. Widespread Long Noncoding RNAs as Endogenous Target Mimics for MicroRNAs in Plants. Plant Physiology. 2013 Apr; vol. 161 no. 4 1875-1884.

11. Shulan Fu, Zhenling Lv, Zhi Gao, Hua-Jun Wu, …, Xiu-Jie Wang, James A Birchler, Fangpu Han. De novo centromere formation on a chromosome fragment in maize. Proc Natl Acad Sci U S A. 2013 Apr; vol. 110 no. 15 6033-6036.

10. Bing Zhang, Zhenling Lv, …, Hua-Jun Wu, Zhi Gao, Xiu-Jie Wang and Fangpu Han. Formation of a Functional Maize Centromere after Loss of Centromeric Sequences and Gain of Ectopic Sequences. Plant Cell. 2013 Jun;25(6):1979-89.

9. Hua-Jun Wu*, Zhi-Min Wang*, Meng Wang and Xiu-Jie Wang. Widespread Long Noncoding RNAs as Endogenous Target Mimics for MicroRNAs in Plants. Plant Physiology. 2013 Apr; vol. 161 no. 4 1875-1884.

8. Hong-Qing Ling, Shancen Zhao, Dongcheng Liu, Junyi Wang, …, Hua-Jun Wu, …, Jian Wang, Huanming Yang, Zhensheng Li, Daowen Wang, Aimin Zhang, Jun Wang. Draft genome of the wheat A-genome progenitorTriticum urartu. Nature. 2013 Apr 4;496(7443):87-90.

2012

7. Wei Li, Ling Shuai, Haifeng Wan, Mingzhu Dong, …, Hua-Jun Wu, Zhonghua Liu, Lei Liu, Liu Wang, Xiu-Jie Wang, Xiao-Yang Zhao, Qi Zhou. Androgenetic haploid embryonic stem cells produce live transgenic mice. Nature. 2012 Oct 18;490(7420):407-11.

6. Hua-Jun Wu, Ying-Ke Ma, Tong Chen, Meng Wang and Xiu-Jie Wang. psRobot: a web-based plant small RNA analysis toolbox. Nucleic Acids Research. 2012 Jul;40(W1):W22-8.

5. Hua-Jun Wu, Zhonghui Zhang, Junyi Wang, Dong-Ha Oh, Maheshi Dassanayake, Binghang Liu, Quanfei Huang*, …, Jun Wang, Chengcai Chu, Shouyi Chen, Hans J Bohnert, Jian-kang Zhu, Xiu-Jie Wang and Qi Xie. Insights into salt tolerance from the genome of Thellungiella salsuginea. Proc Natl Acad Sci U S A. 2012 Jul 24;109(30):12219-24.

4. Chao Sheng, Qinyuan Zheng, Jianyu Wu, …, Hua-Jun Wu, …, Xiu-Jie Wang, Zhiguo Chen, Qi Zhou. Direct reprogramming of Sertoli cells into multipotent neural stem cells by defined factors. Cell Research. 2012 Jan;22(1):208-18.

2011

3. Man Tong, Zhuo Lv, Lei Liu, …, Hua-Jun Wu, …, Xiu-Jie Wang, Jia-Hao Sha, Qi Zhou. Mice generated from tetraploid complementation competent iPS cells show similar developmental features as those from ES cells but are prone to tumorigenesis. Cell Research. 2011 Nov;21(11):1634-7.

2010

2. Lei Liu, Guan-Zheng Luo, Wei Yang, Xiaoyang Zhao, …, Hua-Jun Wu, Liu Wang, Xiu-Jie Wang and Qi Zhou. Activation of the imprinted Dlk1-Dio3 region correlates with pluripotency levels of mouse stem cells. J. Biol. Chem. 2010 Jun 18;285(25):19483-90.

2009

1. Hada Wuriyanghan, Bo Zhang, …, Hua-Jun Wu, …, Xiu-Jie Wang, Shou-Yi Chen, and Jin-Song Zhang. The Ethylene Receptor ETR2 Delays Floral Transition and Affects Starch Accumulation in Rice. Plant Cell. 2009 May;21(5):1473-94.